A reference on methods to generate pharmacokinetic and safety profiles of drug candidates, and how they must be balanced against one other for the best selection of candidates for further development. It presents an introduction to the necessities of filtering and risk assessment of potential new dr[...]
Offers information a drug researcher needs to know about epigenetic mechanisms of disease. This book surveys the methodologies for finding and validating drug candidates that act via epigenetic mechanisms. It also surveys known and suspected drug targets within the epigenetic machinery.[...]