Intended for senior-level and first-year graduate courses in Tissue Engineering, in departments of bioengineering; and for students researching tissue replacement and restorations. This book provides a conceptual framework that includes exposure to all the necessary background material in all areas.[...]
Genome sequences are now available that enable us to determine the biological components that make up a cell or an organism. The discipline of systems biology examines how these components interact and form networks, and how the networks generate whole cell functions corresponding to observable phen[...]
Biophysical models have been used in biology for decades, but they have been limited in scope and size. In this book, Bernhard O. Palsson shows how network reconstructions that are based on genomic and bibliomic data, and take the form of established stoichiometric matrices, can be converted into dy[...]
Recent technological advances have enabled comprehensive determination of the molecular composition of living cells. The chemical interactions between many of these molecules are known, giving rise to genome-scale reconstructed biochemical reaction networks underlying cellular functions. Mathematica[...]