Mass Spectrometry

The first edition of this highly successful textbook has been acclaimed for its comprehensive coverage, its accuracy, and its many excellent illustrations and photographs. Completely revised end extended, this second edition now includes three new chapters on tandem mass spectrometry, interfaces for [...]
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The first edition of this highly successful textbook has been acclaimed for its comprehensive coverage, its accuracy, and its many excellent illustrations and photographs. Completely revised end extended, this second edition now includes three new chapters on tandem mass spectrometry, interfaces for sampling at atmospheric pressure, and inorganic mass spectrometry. Coverage of bioanalytical applications such as proteomics is extended. Useful both as a textbook and as a reference source for the experienced user, this book is tailored for students and professionals. It will guide them from the basics to the successful application of mass spectrometry. Starting from the very principles of gas-phase ion chemistry and isotopic properties, it leads through the design of mass analyzers and ionization methods in use to mass spectral interpretation and coupling techniques. Step by step the readers will learn how mass spectrometry works and what it can do as a powerful tool in their hands. The book offers a balanced mixture of practice-oriented information and theoretical background as well as numerous references, clear and informative illustrations, and useful data tables. Problems and solutions are accessible via a special website. TOC:Introduction.- Gas Phase Ion Chemistry.- Isotopes.- Instrumentation.- Electron Ionization.- Fragmentation of Organic Ions and Interpretation of EI Mass Spectra.- Chemical Ionization.- Field Ionization and Field Desorption.- Tandem Mass Spectrometry.- Fast Atom Bombardment.- Matrix-Assisted Laser Desorption/Ionization.- Electrospray Ionization.- Interfaces for Sampling at Atmospheric Pressure.- Hyphenated Methods.- Inorganic Mass Spectrometry.- Appendices: List of Akronyms.- Periodic Table of the Elements.- Building Blocks of Biopolymers.