Down Syndrome: From Understanding the Neurobiology to Therapy

Down syndrome (DS) is the most common example of neurogenetic aneuploid disorder leading to mental retardation. This title discusses comparative genomics, gene expression atlases of the brain, network genetics, engineered mouse models and applications to human and mouse behavioral and cognitive phen [...]
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Down syndrome (DS) is the most common example of neurogenetic aneuploid disorder leading to mental retardation. This title discusses comparative genomics, gene expression atlases of the brain, network genetics, engineered mouse models and applications to human and mouse behavioral and cognitive phenotypes.