Redox Signaling and Regulation in Biology and Medicine

For the human body, redox processes are a two-edged sword: We need them to burn our food, to provide the body with energy, to fight off invading organisms and to transmit biochemical signals between and within our cells. On the other hand, redox processes can attack and degrade cells and their const [...]
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For the human body, redox processes are a two-edged sword: We need them to burn our food, to provide the body with energy, to fight off invading organisms and to transmit biochemical signals between and within our cells. On the other hand, redox processes can attack and degrade cells and their constituents if they occur in the wrong context or place. To keep redox events in check, cells have evolved a complex regulatory and feedback network. Consequently, malfunctions or impairments in redox control are a cause of disease and greatly contribute to the aging of cells, tissues, and organs. This first entry-level guide to the fascinating field of redox signaling and regulation fills the knowledge gap in existing biochemistry and biology textbooks. In an easily accessible manner, the authors integrate the chemistry, biochemistry, cell biology and medical implications of intracellular redox processes, demonstrating that complex science can be presented in a clear and even entertaining manner. Perfect for students and researchers, this is an equally valuable addition to courses in biochemistry, molecular biology, cell biology, and human physiology.