DNA Methylation Microarrays

Written from the perspective of an analyst who interacts closely with biology colleagues who have only minimal knowledge of statistics and programming, "DNA Methylation Microarrays" provides a solid understanding of methodological foundations and enables critical thinking for advanced studies. Using [...]
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Written from the perspective of an analyst who interacts closely with biology colleagues who have only minimal knowledge of statistics and programming, "DNA Methylation Microarrays" provides a solid understanding of methodological foundations and enables critical thinking for advanced studies. Using graphics to illustrate the results, the book presents examples based on real biological data from a variety of cellular samples with array hybridizations performed in the laboratory. It covers quality control, experimental design, normalization, significant differential methylation, clustering, dependence networks, and online annotations.