Mechanisms of Memory

'Sweatt has done a superb and scholarly job of telling the story of this field.' - Howard Eichenbaum, Editor in Chief Hippocampus, Boston University 'It is definitely worth publishing a second edition. David is a leader in the field. The book is well written and has lots of nice figures making it ea [...]
Visa längre beskrivning

'Sweatt has done a superb and scholarly job of telling the story of this field.' - Howard Eichenbaum, Editor in Chief Hippocampus, Boston University 'It is definitely worth publishing a second edition. David is a leader in the field. The book is well written and has lots of nice figures making it easy to teach from.' - Daniel Johnston, Director, Center for Learning and Memory; Director, Institute for Neuroscience, University of Texas at Austin Sweatt is an outstanding writer and conveyer of complex concepts. He engages readers with lots of examples and detailed explanations for the most difficult material. It is a superb book for its audience.' - Laura Flashman, Associate Professor of Psychiatry; Director, Neuropsychology Program, Dartmouth Hitchcock Medical Center, Lebanon, NH Human learning and memory is likely the most highly evolved and sophisticated biological process in existence. Many who work on the cellular and molecular processes of learning and memory are tempted to throw up their hands in frustration and conclude that the problem is insoluble.Mechanisms of Memory 2nd edition completely revises this still unique reference to make the book more accessible, full updated with the many new advances in molecular neuroscience of the past six years, and expanded in scope to include four new chapters on the role of memory in neurological and psychiatric disorders and very promising approaches to translate the our knowledge about the molecular basis of memory to new treatment options in clinical practice. The book presents the complex puzzle of the molecular basis of memory in an integrated way that is understandable and accessible to students of Neuroscience, Psychology, Molecular Biology, while still being of great value to active scientists in the field. Sweatt creates a framework of thinking about synaptic plasticity and memory at the molecular level, incorporating this extreme biochemical complexity into our thinking about memory. Five years on from the publication of the first edition, this is still the only book on the market that covers cellular and molecular mechanisms of memory to this level of detail.The book will be a valuable reference for graduate students taking a memory course in any of the disciplines of psychology, neuroscience or biology. It will be of use to students interested in the medical professions and graduate students interested in translational aspects of basic memory research. Systematic linkage of the chapters to the more in depth reviews in Elsevier's comprehensive reference work Learning and Memory (Feb 2008, eds Byrne, Sweatt, Roediger, Menzel, Eichenbaum) will make the book a wonderful portal to the wide spread and complex molecular literature. * Five new chapters cover human learning and memory, the molecular and cellular basis of associative learning, Aplysia non-associative learning, the NMDA receptor, and experimental design. * Provides the latest research information on how disorders of molecular events in memory impact major neurological diseases, and how new treatments can thus be approached * Each chapter includes suggested readings for journal clubs, more introductory material for students, extensive cross-referencing to detailed, current reviews in Learning and Memory: A Comprehensive Reference (Academic Press, 2008).* A companion website provides figures in PowerPoint format plus additional, detailed further reading references * Extensively illustrated throughout with many new, full color figures to help explain key concepts * This edition includes new information about epigenetic mechanisms in memory function, glutamate receptor trafficking, invertebrate associative learning, working memory and the prefrontal cortex, motor learning, protein synthesis in memory and learning disabilities. * Furthermore, it covers new treatments of gene regulation in memory, place cells and grid cells, human neuroimaging, human motor learning and associative conditioning, Alzheimer's disease and learning disabilities.